Tag Animal research
Chemical signal puts bacteria on path to a bright future with squid host
A tiny molecule found among microscopic bacteria living in a mutually beneficial partnership with golf-ball-sized squid may give scientists a lead on how the bacteria are able to act in concert as a helpful colony instead of millions of individual freeloaders.
Researchers find a better way to measure consciousness
A new study of brain activity could prevent the potential trauma of patients under anesthesia regaining some awareness during medical procedures.
Individualized brain cell grafts reverse Parkinson’s symptoms in monkeys
UW researchers say the stem cell treatment is an "extremely powerful" step toward a treatment for millions of human Parkinson’s patients.
A new way to help the immune system fight back against cancer
"We believe we are launching a new cancer therapy field here," says Jamey Weichert, professor of radiology. "It’s very exciting, and the research team is incredible.”
Gene-edited monkey embryos give researchers new way to study HIV cure
A gene that cured a man of HIV a decade ago has been successfully added to developing monkey embryos in an effort to study more potential treatments for the disease.
Early mutation in SARS-CoV-2 virus in Europe led to its domination worldwide
A study shows that the mutant virus is more easily transmitted and grows better within hosts, likely aiding its dominance. The mutation, researchers say, should not interfere with the effectiveness of vaccines against the virus.
First relatives of rubella virus discovered in bats in Uganda and mice in Germany
Neither of the new viruses is known to infect people, but the findings reinforce the important work scientists are undertaking to study the effects of a changing environment on human and animal diseases.
Stem cells can repair Parkinson’s-damaged circuits in mouse brains
UW neuroscientists led by Su-Chun Zhang found that neurons derived from stem cells can connect with native neurons and restore motor functions. But more research is needed to translate the findings from mice to people.
New vaccine strategy harnesses ‘foot soldier’ T-cells to provide protection against influenza
Researchers believe the same approach can be applied to several other respiratory pathogens, including the novel coronavirus that causes COVID-19.
PETA misrepresents UW–Madison lab
Leaders and staff at UW–Madison, including people who care for and provide oversight of our animals, take seriously our responsibility to care for animals in research.
New COVID-19 clinical trials at UW–Madison and UW Health will study antibody approach
The trials center around an “antibody cocktail” called REGN-COV2, which was created by the New York-based pharmaceutical company Regeneron.
Tiny mineral particles are better vehicles for promising gene therapy
UW–Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination — including a COVID-19 vaccine that has advanced to clinical trials.
Hamsters develop protective immunity to COVID-19 and are protected by convalescent sera
The animals are useful to researchers trying to understand SARS-CoV-2 and in the evaluation of vaccines, treatments and drugs against the disease it causes.
Study confirms cats can become infected with and may transmit COVID-19 to other cats
Researchers advise that people with symptoms avoid contact with cats, and cat owners should keep their pets indoors to limit contact with other people and animals.
Research on viral junk, quicker drug testing could help outflank coronaviruses
Researchers hope to better understand how coronaviruses enter cells, spread, and cause varying immune responses in different individuals.
Combining mouse and human data uncovers new gene regulating cholesterol
Work by Brian Parks and collaborators provides a new target for understanding the genetic risk of high cholesterol, which is linked to heart disease.
Wisconsin State Laboratory of Hygiene works with campus partners to test for COVID-19
Although the global surge in demand has made it more difficult in many places, WSLH’s colleagues at the university have pitched in to keep testing available in Wisconsin.
UW–Madison, FluGen, Bharat Biotech to develop CoroFlu, a coronavirus vaccine
Refinement of the CoroFlu vaccine concept and testing in laboratory animal models at UW–Madison is expected to take three to six months. CoroFlu could be in human clinical trials by fall, 2020.
Deleting a gene prevents Type 1 diabetes in mice by disguising insulin-producing cells
The cellular sleight of hand, says biomolecular chemist Feyza Engin, may also suggest ways to prevent other diseases in which the immune system targets the body’s own cells.
Molds damage the lung’s protective barrier to spur future asthma attacks
A UW–Madison study provides a new avenue of research for understanding and potentially preventing the development of asthma, which affects 25 million Americans.