Tag Animal research
New drug delivery method harnesses clotting to target anti-cancer drugs at tumors
Researchers found that in mice that received the engineered proteins via intravenous injections, the proteins led to clot formation almost exclusively within tumors, with only very limited thrombosis occurring elsewhere.
UW researchers identify cell type that could be key to preventing marrow transplant complication
UW researchers at the Carbone Cancer Center have identified the cells that can cause graft-versus-host disease, the most common complication of bone marrow transplants.
New funding to protect bats from fungal epidemic hinges on UW–Madison discoveries
Researchers will investigate a multi-pronged approach to protecting wild bats against Pseudogymnoascus destructans, the fungus that causes white-nose syndrome.
New nanocapsules deliver therapy brain-wide, edit Alzheimer’s gene in mice
UW researchers have found a way to move gene therapies through the blood-brain barrier, a crucial step for brain-wide CRISPR treatments of disorders like Alzheimer's and Parkinson's disease.
Probiotic ‘backpacks’ show promise for treating inflammatory bowel diseases
UW researchers demonstrate just how much promise some well-equipped bacteria hold for improved inflammatory bowel disease treatments.
Brain-gut connection may reveal way to prevent cocaine addiction
Cocaine disrupts the balance of microbes in the guts of mice, part of a cycle of waxing and waning neurochemicals that can enhance the drug’s effects in the brain. But the same chemicals may also be harnessed to prevent addiction, according to new research.
Study shows differences between brains of primates — humans, other apes and monkeys — are small but significant
The cellular differences between these species may illuminate steps in their evolution and how those differences can be implicated in disorders, such as autism and intellectual disabilities, seen in humans.
Wild primate virus has pandemic potential should it jump the species barrier, shows study
New research demonstrates the potential for a family of viruses in African primates to jump the species barrier to humans.
Monitoring an invasion: Where are jumping worms now?
Invasive jumping worms threaten soil health in Wisconsin, including in Dane County where the population has infested the University of Wisconsin–Madison Arboretum. Brad Herrick leads crews of volunteers to survey for the worms so that researchers can study their movements and possibly find ways to halt their spread.
New study allows scientists to test therapeutics for rare disease affecting young children
The team used CRISPR gene editing technology to create in rat embryos the mutations that lead to HSP. This allowed them to study how the disease progresses from early development and monitor the progression of symptoms after birth.
Avian influenza persists as migration peaks
The persistence of highly pathogenic avian influenza in wild and domestic birds through the summer months points to a likely rise in cases this fall, according to Wisconsin Veterinary Diagnostic Laboratory Director Keith Poulsen.
Creating stem cells from minipigs offers promise for improved treatments
A new study from Wan-Ju Li's lab in the UW–Madison Stem Cell & Regenerative Medicine Center advances research into reparative osteoarthritis therapies using stem cells derived from the ears of miniature pigs.
Chancellor Mnookin tours dairy farm, highlights research efforts
The visit to two dairy farms highlighted the Dairy Innovation Hub, a partnership that conducts research and offers support to Wisconsin's dairy industry.
How a small, unassuming fish helps reveal gene adaptations
New UW–Madison research sheds light on the genetic basis by which stickleback populations inhabiting ecosystems near each other developed a strong immune response to tapeworm infections, and how some populations later came to tolerate the parasites.
See-through zebrafish, new imaging method put blood stem cells in high-resolution spotlight
This new technique will aid researchers as they develop therapies for blood diseases and cancers.
New understanding of ‘superantigens’ could lead to improved staph infection treatments
Researchers at the UW School of Veterinary Medicine explain that the bacterium Staphylococcus aureus not only causes illness, but undermines the body’s ability to heal — a finding that could point toward new approaches to fighting infection.
New nanoparticles aid sepsis treatment in mice
In new research published today, UW–Madison researchers reported a new nanoparticle-based treatment for sepsis that delivers anti-inflammatory molecules and antibiotics.
Experimental COVID-19 vaccine provides mutation-resistant T cell protection in mice
A second line of defense — the immune system’s T cells — may offer protection from COVID-19 even when vaccine-induced antibodies no longer can, according to new research out of the University of Wisconsin School of Veterinary Medicine.
UW Veterinary Care offers rabbit vaccine against highly contagious, fatal disease
The clinic is one of about a dozen animal hospitals in the state to offer the vaccine and part of a growing effort nationally to encourage rabbit owners to seek vaccination.
Biodegradable gel boosts immune system’s attack on several cancers in mice
The gel, tested in mice, releases drugs and special antibodies that simultaneously deplete immune-blocking cells called macrophages from the surgical site and activate T cells so they can attack cancer.